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Merck

P2RX3

purinergic receptor P2X, ligand-gated ion channel, 3

Synonyms:
P2X3
Species:
UniProtKB ID:
Gene ID:
  • Human(5024) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]
  • Mouse(228139) purinergic receptor P2X, ligand-gated ion channel, 3
  • Rat(81739) purinergic receptor P2X, ligand-gated ion channel, 3
  • domestic guinea pig(100722959) purinergic receptor P2X, ligand-gated ion channel, 3
  • sheep(101104779) purinergic receptor P2X, ligand-gated ion channel, 3
  • chicken(428856) purinergic receptor P2X, ligand-gated ion channel, 3
  • cow(530468) purinergic receptor P2X, ligand-gated ion channel, 3
  • dog(448782) purinergic receptor P2X, ligand-gated ion channel, 3
  • naked mole-rat(101709018) purinergic receptor P2X, ligand-gated ion channel, 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Purinergic Receptor P2X3 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
immunohistochemistry
western blot
Anti-P2RX3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human P2RX3,
Species
human
MISSION® esiRNA, targeting mouse P2rx3,
Species
mouse