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Merck

OLR1

oxidized low density lipoprotein (lectin-like) receptor 1

Synonyms:
CLEC8A, LOX1, LOXIN, SCARE1, SLOX1
Species:
UniProtKB ID:
Gene ID:
  • Human(4973) Summary: This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
  • Mouse(108078) oxidized low density lipoprotein (lectin-like) receptor 1
  • Rat(140914) oxidized low density lipoprotein (lectin-like) receptor 1
  • naked mole-rat(101710182) oxidized low density lipoprotein (lectin-like) receptor 1
  • domestic guinea pig(100725301) oxidized low density lipoprotein (lectin-like) receptor 1
  • domestic cat(101086238) oxidized low density lipoprotein (lectin-like) receptor 1
  • dog(486694) oxidized low density lipoprotein (lectin-like) receptor 1
  • sheep(101117918) oxidized low density lipoprotein (lectin-like) receptor 1
  • cow(281368) oxidized low density lipoprotein (lectin-like) receptor 1

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Mouse Olr1 / Oxidized Low-density Lipoprotein Receptor 1 ELISA Kit, ,
Species
mouse
Human LOX-1 / OLR1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Rhesus Macaque LOX-1 ELISA, for serum, plasma and cell culture supernatants,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-OLR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human OLR1,
Species
human