NSD1
nuclear receptor binding SET domain protein 1
Synonyms:
ARA267, KMT3B, SOTOS, SOTOS1, STO
Species:
Human NSD1 (64324), Mouse Nsd1 (18193), Rat Nsd1 (306764), chicken NSD1 (416214), dog NSD1 (489094), domestic guinea pig Nsd1 (100727598), naked mole-rat Nsd1 (101698401), Horse NSD1 (100058570), Domestic Rabbit NSD1 (100355926), domestic cat NSD1 (101100618) ...More
UniProtKB ID:
Gene ID:
- Human(64324) Summary: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18193) nuclear receptor-binding SET-domain protein 1
- Rat(306764) nuclear receptor binding SET domain protein 1
- chicken(416214) nuclear receptor binding SET domain protein 1
- dog(489094) nuclear receptor binding SET domain protein 1
- domestic guinea pig(100727598) nuclear receptor binding SET domain protein 1
- naked mole-rat(101698401) nuclear receptor binding SET domain protein 1
- Horse(100058570) nuclear receptor binding SET domain protein 1
- Domestic Rabbit(100355926) nuclear receptor binding SET domain protein 1
- domestic cat(101100618) nuclear receptor binding SET domain protein 1
- cow(540197) nuclear receptor binding SET domain protein 1
- sheep(101120917) nuclear receptor binding SET domain protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NSD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-NSD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-NSD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-NSD1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species