Skip to Content
Merck

NFKBIB

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Synonyms:
IKBB, TRIP9
Species:
UniProtKB ID:
Gene ID:
  • Human(4793) Summary: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
  • Mouse(18036) nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
  • Rat(81525) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • dog(484519) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • domestic cat(101099259) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • chicken(100858419) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • domestic guinea pig(100734800) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • naked mole-rat(101717375) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • cow(525408) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • sheep(101113618) nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IκB-β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Anti-NFKBIB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-phospho-IκB-β (pThr19) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-NFKBIB (pSer23) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry

Proteins

Product Number
Description
Species
I?Bβ , GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nfkbib,
Species
mouse
MISSION® esiRNA, targeting human NFKBIB,
Species
human