Skip to Content
Merck

MRPS18B

mitochondrial ribosomal protein S18B

Synonyms:
C6orf14, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt
Species:
UniProtKB ID:
Gene ID:
  • Human(28973) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008]
  • Mouse(66973) mitochondrial ribosomal protein S18B
  • Rat(294230) mitochondrial ribosomal protein S18B
  • domestic guinea pig(100722297) mitochondrial ribosomal protein S18B
  • Zebrafish(550455) mitochondrial ribosomal protein S18B
  • cow(510824) mitochondrial ribosomal protein S18B
  • dog(474827) mitochondrial ribosomal protein S18B
  • sheep(101107394) mitochondrial ribosomal protein S18B
  • domestic cat(101093104) mitochondrial ribosomal protein S18B
  • fruit fly(35299) mitochondrial ribosomal protein S18B
  • naked mole-rat(101708525) mitochondrial ribosomal protein S18B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MRPS18B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MRPS18B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MRPS18B,
Species
human