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Merck

MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(4242) Summary: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009]
  • Mouse(17305) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • Rat(315119) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • domestic cat(101097256) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • cow(505267) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • sheep(101103554) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • chicken(418042) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • Zebrafish(493633) manic fringe homolog
  • dog(610303) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • naked mole-rat(101722987) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
  • domestic guinea pig(100731745) MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MFNG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MFNG,
Species
human
MISSION® esiRNA, targeting mouse Mfng,
Species
mouse