KLK2
kallikrein-related peptidase 2
Synonyms:
KLK2A2, hGK-1, hK2
Species:
UniProtKB ID:
Gene ID:
- Human(3817) Summary: This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]
- domestic guinea pig(100716976) kallikrein-related peptidase 2
- dog(403967) kallikrein-related peptidase 2
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