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Merck

IRF4

interferon regulatory factor 4

Synonyms:
LSIRF, MUM1, NF-EM5
Species:
UniProtKB ID:
Gene ID:
  • Human(3662) Summary: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
  • Mouse(16364) interferon regulatory factor 4
  • Rat(291100) interferon regulatory factor 4
  • naked mole-rat(101705637) interferon regulatory factor 4
  • domestic guinea pig(100719564) interferon regulatory factor 4
  • sheep(101111234) interferon regulatory factor 4
  • cow(506141) interferon regulatory factor 4
  • chicken(374179) interferon regulatory factor 4
  • domestic cat(101089438) interferon regulatory factor 4
  • Horse(100049827) interferon regulatory factor 4
  • Horse(100068881) interferon regulatory factor 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IRF-4 Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-Irf4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14615, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MUM1/IRF4 antibody, Rabbit monoclonal, clone SP114, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-IRF4 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-IRF4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IRF4,
Species
human