HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
Synonyms:
5-HT2A, HTR2
Species:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
UniProtKB ID:
Gene ID:
- Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
- Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
- cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A
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Small Molecule - Agonist
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Description
Species
Small Molecule - Allosteric Modulator
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Description
Species
Small Molecule - Antagonist
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Description
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Antibodies
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Description
Species Reactivity
Application
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-HTR2A, affinity isolated antibody,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Blocker
Small Molecule - Inhibitor
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Description
Species
Trazodone hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Species
human
Small Molecule - Ligand
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Description
Species
Small Molecule - Metabolite
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Description
Species
Small Molecule - Mixed Agonist/Antagonist
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Description
Species
Small Molecule - Precursor
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Description
Species
esiRNA
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Description
Species