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Merck

HSPB8

heat shock 22kDa protein 8

Synonyms:
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Species:
UniProtKB ID:
Gene ID:
  • Human(26353) Summary: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
  • Mouse(80888) heat shock protein 8
  • Rat(113906) heat shock protein B8
  • sheep(101108164) heat shock 22kDa protein 8
  • domestic cat(101093804) heat shock 22kDa protein 8
  • Zebrafish(791580) heat shock protein, alpha-crystallin-related, b8
  • chicken(416988) heat shock 22kDa protein 8
  • domestic guinea pig(100734199) heat shock 22kDa protein 8
  • naked mole-rat(101707078) heat shock 22kDa protein 8
  • dog(403553) heat shock 22kDa protein 8
  • cow(539524) heat shock 22kDa protein 8

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HSPB8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-HSPB8/HSP22 Antibody, clone 3K10W1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
Heat Shock Protein 22 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HSPB8,
Species
human
MISSION® esiRNA, targeting mouse Hspb8,
Species
mouse