HRH1
histamine receptor H1
Synonyms:
H1-R, hisH1
Species:
Human HRH1 (3269), Mouse Hrh1 (15465), Rat Hrh1 (24448), naked mole-rat Hrh1 (101715481), domestic cat HRH1 (101088314), domestic guinea pig Hrh1 (100135539), chicken HRH1 (100858928), domestic guinea pig Hrh1 (100730517), cow HRH1 (281231), dog HRH1 (403813) ...More
UniProtKB ID:
Gene ID:
- Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(15465) histamine receptor H1
- Rat(24448) histamine receptor H 1
- naked mole-rat(101715481) histamine receptor H1
- domestic cat(101088314) histamine receptor H1
- domestic guinea pig(100135539) histamine receptor H1
- chicken(100858928) histamine receptor H1
- domestic guinea pig(100730517) histamine receptor H1
- cow(281231) histamine receptor H1
- dog(403813) histamine receptor H1
- Zebrafish(735302) histamine receptor H1
- Horse(100034110) histamine receptor H1
- sheep(101121717) histamine receptor H1
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Small Molecule - Agonist
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Small Molecule - Antagonist
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Small Molecule - Blocker
Small Molecule - Inhibitor
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Small Molecule - Ligand
Small Molecule - Metabolite
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Small Molecule - Mixed Agonist/Antagonist
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