GREM2
gremlin 2, DAN family BMP antagonist
Synonyms:
CKTSF1B2, DAND3, PRDC
Species:
Human GREM2 (64388), Mouse Grem2 (23893), Rat Grem2 (289264), chicken GREM2 (421507), Zebrafish grem2 (550399), domestic guinea pig Grem2 (100731124), dog GREM2 (490367), domestic cat GREM2 (101096531)
UniProtKB ID:
Gene ID:
- Human(64388) Summary: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]
- Mouse(23893) gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
- Rat(289264) gremlin 2
- chicken(421507) gremlin 2
- Zebrafish(550399) gremlin 2, cysteine knot superfamily
- domestic guinea pig(100731124) gremlin 2, DAN family BMP antagonist
- dog(490367) gremlin 2
- domestic cat(101096531) gremlin 2
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