EMX2
empty spiracles homeobox 2
Human EMX2 (2018), Mouse Emx2 (13797), Rat Emx2 (499380), sheep EMX2 (101105042), cow EMX2 (523601), dog EMX2 (610697), domestic cat EMX2 (101087011), chicken EMX2 (423923), domestic guinea pig Emx2 (100718552), Zebrafish emx2 (30537)
- Human(2018) Summary: This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.[provided by RefSeq, Sep 2009]
- Mouse(13797) empty spiracles homeobox 2
- Rat(499380) empty spiracles homeobox 2
- sheep(101105042) empty spiracles homeobox 2
- cow(523601) empty spiracles homeobox 2
- dog(610697) empty spiracles homeobox 2
- domestic cat(101087011) empty spiracles homeobox 2
- chicken(423923) empty spiracles homeobox 2
- domestic guinea pig(100718552) empty spiracles homeobox 2
- Zebrafish(30537) empty spiracles homeobox 2
- naked mole-rat(101724841) empty spiracles homeobox 2
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