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Merck

CSE1L

CSE1 chromosome segregation 1-like (yeast)

Synonyms:
CAS, CSE1, XPO2
Species:
UniProtKB ID:
Gene ID:
  • Human(1434) Summary: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(110750) chromosome segregation 1-like (S. cerevisiae)
  • Rat(362273) CSE1 chromosome segregation 1-like (yeast)
  • Zebrafish(30707) chromosome segregation 1-like (S. cerevisiae)
  • chicken(419212) CSE1 chromosome segregation 1-like (yeast)
  • dog(477257) CSE1 chromosome segregation 1-like (yeast)
  • Horse(100056886) CSE1 chromosome segregation 1-like (yeast)
  • domestic guinea pig(100725108) CSE1 chromosome segregation 1-like (yeast)
  • cow(518622) CSE1 chromosome segregation 1-like (yeast)
  • sheep(101120005) CSE1 chromosome segregation 1-like (yeast)
  • naked mole-rat(101705453) CSE1 chromosome segregation 1-like (yeast)
  • domestic cat(101081375) CSE1 chromosome segregation 1-like (yeast)

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Exportin 2 (XPO2) antibody produced in rabbit, ,
Species Reactivity
Application
immunohistochemistry
western blot
Anti-CSE1L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CSE1L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
KD-Validated Anti CSE1L Antibody, clone 23GB3515, Rabbit Monoclonal, clone 23GB3515, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human, rat
Application
flow cytometry
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CSE1L,
Species
human
MISSION® esiRNA, targeting mouse Cse1l,
Species
mouse