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Merck

COL2A1

collagen, type II, alpha 1

Synonyms:
ANFH, AOM, COL11A3, SEDC
Species:
UniProtKB ID:
Gene ID:
  • Human(1280) Summary: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12824) collagen, type II, alpha 1
  • Rat(25412) collagen, type II, alpha 1
  • Horse(791241) collagen, type II, alpha 1
  • Domestic Rabbit(100009005) collagen, type II, alpha 1
  • domestic cat(101087493) collagen, type II, alpha 1
  • Goat(100860743) collagen, type II, alpha 1
  • dog(403826) collagen, type II, alpha 1
  • chicken(395069) collagen, type II, alpha 1
  • cow(407142) collagen, type II, alpha 1
  • domestic guinea pig(100733907) collagen, type II, alpha 1
  • sheep(100196905) collagen, type II, alpha 1
  • naked mole-rat(101707672) collagen, type II, alpha 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Collagen II antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Collagen Type II Antibody, clone 1K11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, chicken, equine, feline, human, monkey, porcine
Application
ELISA
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Collagen from bovine tracheal cartilage, Bornstein and Traub Type II, powder,
Species
cow
Collagen from bovine nasal septum, Bornstein and Traub Type II, powder,
Species
cow
Collagen from chicken sternal cartilage, Type II (Miller), powder, BioReagent, suitable for cell culture,
Species
chicken
Collagen, from bovine flexor tendon,
Species
cow
Collagen from calf skin, Bornstein and Traub Type I, (0.1% solution in 0.1 M acetic acid), aseptically processed, BioReagent, suitable for cell culture,
Species
cow

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Col2a1,
Species
mouse