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Merck

CFL2

cofilin 2 (muscle)

Synonyms:
NEM7
Species:
Human CFL2 (1073), Mouse Cfl2 (12632), Rat Cfl2 (366624), Zebrafish cfl2 (403001), domestic cat CFL2 (101083089), cow CFL2 (539332), domestic guinea pig Cfl2 (100727405), dog CFL2 (490649), sheep CFL2 (101118388), chicken CFL2 (423320)
UniProtKB ID:
Q9Y281, G3V5P4
Gene ID:
  • Human(1073) Summary: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
  • Mouse(12632) cofilin 2, muscle
  • Rat(366624) cofilin 2, muscle
  • Zebrafish(403001) cofilin 2 (muscle)
  • domestic cat(101083089) cofilin 2 (muscle)
  • cow(539332) cofilin 2 (muscle)
  • domestic guinea pig(100727405) cofilin 2 (muscle)
  • dog(490649) cofilin 2 (muscle)
  • sheep(101118388) cofilin 2 (muscle)
  • chicken(423320) cofilin 2 (muscle)

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4500148
Anti-Cofilin antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
HPA045599
Anti-CFL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB4300577
Anti-CCFL1/CFL2 (Ab-88) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB4300263
Anti-phospho-CFL1/CFL2 (pTyr88) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
C8736
Anti-Cofilin antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
immunofluorescence
microarray
western blot

esiRNA

Product Number
Description
Species
EMU064621
MISSION® esiRNA, targeting mouse Cfl2,
Species
mouse
EHU061971
MISSION® esiRNA, targeting human CFL2,
Species
human