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Merck

BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein)

Synonyms:
BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, EVI9, HBFQTL5, ZNF856
Species:
Human BCL11A (53335), Mouse Bcl11a (14025), Rat Bcl11a (305589), Domestic Rabbit BCL11A (100355522), sheep BCL11A (101119124), domestic guinea pig Bcl11a (100734801), dog BCL11A (481381), chicken BCL11A (421199), cow BCL11A (538680), domestic cat BCL11A (101098704)
UniProtKB ID:
Q9H165, D6W5D7, Q86W14, Q8WU92, Q96JL6, Q9H163, Q9H164, Q9H3G9
Gene ID:
  • Human(53335) Summary: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14025) B cell CLL/lymphoma 11A (zinc finger protein)
  • Rat(305589) B-cell CLL/lymphoma 11A (zinc finger protein)
  • Domestic Rabbit(100355522) B-cell CLL/lymphoma 11A (zinc finger protein)
  • sheep(101119124) B-cell CLL/lymphoma 11A (zinc finger protein)
  • domestic guinea pig(100734801) B-cell CLL/lymphoma 11A (zinc finger protein)
  • dog(481381) B-cell CLL/lymphoma 11A (zinc finger protein)
  • chicken(421199) B-cell CLL/lymphoma 11A (zinc finger protein)
  • cow(538680) B-cell CLL/lymphoma 11A (zinc finger protein)
  • domestic cat(101098704) B-cell CLL/lymphoma 11A (zinc finger protein)

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Antibodies

Product Number
Description
Species Reactivity
Application
AMAB91869
Monoclonal Anti-Bcl11A Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13501, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
AMAB91871
Monoclonal Anti-Bcl11A Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13530, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA075941
Anti-BCL11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB5702769
Anti-CTIP1/BCL11A Antibody, clone 3M8M3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
ZRB1518
Anti-Bcl11A Antibody, clone 2C4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU071531
MISSION® esiRNA, targeting mouse Bcl11a,
Species
mouse
EHU145981
MISSION® esiRNA, targeting human BCL11A,
Species
human