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Merck

BAD

BCL2-associated agonist of cell death

Synonyms:
BBC2, BCL2L8
Species:
UniProtKB ID:
Gene ID:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

Product Number
Description
Species
4-Biphenylacetic acid, 98%,
Species
human
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Species
human
Biphenyl-4-carboxylic acid, 95%,
Species
human
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-BAD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-BAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BAD,
Species
human