ALOX5AP
arachidonate 5-lipoxygenase-activating protein
Synonyms:
FLAP
Species:
Human ALOX5AP (241), Mouse Alox5ap (11690), Rat Alox5ap (29624), Horse ALOX5AP (100034178), cow ALOX5AP (613869), dog ALOX5AP (477323), domestic guinea pig Alox5ap (100733727), chicken ALOX5AP (770904), naked mole-rat Alox5ap (101704126), domestic cat ALOX5AP (101090316)
UniProtKB ID:
Gene ID:
- Human(241) Summary: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
- Mouse(11690) arachidonate 5-lipoxygenase activating protein
- Rat(29624) arachidonate 5-lipoxygenase activating protein
- Horse(100034178) arachidonate 5-lipoxygenase-activating protein
- cow(613869) arachidonate 5-lipoxygenase-activating protein
- dog(477323) arachidonate 5-lipoxygenase-activating protein
- domestic guinea pig(100733727) arachidonate 5-lipoxygenase-activating protein
- chicken(770904) arachidonate 5-lipoxygenase-activating protein
- naked mole-rat(101704126) arachidonate 5-lipoxygenase-activating protein
- domestic cat(101090316) arachidonate 5-lipoxygenase-activating protein
- Zebrafish(337376) arachidonate 5-lipoxygenase-activating protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FLAP Antibody, clone 2S7Z0, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-ALOX5AP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species