ALAS1
aminolevulinate, delta-, synthase 1
Synonyms:
ALAS, ALAS3, ALASH, MIG4
Species:
Human ALAS1 (211), Mouse Alas1 (11655), Rat Alas1 (65155), sheep ALAS1 (101112853), Domestic Rabbit ALAS1 (100345847), Goat ALAS1 (100861387), Horse ALAS1 (100060491), cow ALAS1 (534286), domestic cat ALAS1 (101080876), dog ALAS1 (476600) ...More
UniProtKB ID:
Gene ID:
- Human(211) Summary: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
- Mouse(11655) aminolevulinic acid synthase 1
- Rat(65155) aminolevulinate, delta-, synthase 1
- sheep(101112853) aminolevulinate, delta-, synthase 1
- Domestic Rabbit(100345847) aminolevulinate, delta-, synthase 1
- Goat(100861387) aminolevulinate, delta-, synthase 1
- Horse(100060491) aminolevulinate, delta-, synthase 1
- cow(534286) aminolevulinate, delta-, synthase 1
- domestic cat(101080876) aminolevulinate, delta-, synthase 1
- dog(476600) aminolevulinate, delta-, synthase 1
- chicken(552895) aminolevulinate, delta-, synthase 1
- Zebrafish(64608) aminolevulinate, delta-, synthetase 1
- naked mole-rat(101701151) aminolevulinate, delta-, synthase 1
- domestic guinea pig(100723853) aminolevulinate, delta-, synthase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ALAS1 Antibody, clone 2K1G3, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot