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Merck

ADD1

adducin 1 (alpha)

Synonyms:
ADDA
Species:
UniProtKB ID:
Gene ID:
  • Human(118) Summary: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
  • Mouse(11518) adducin 1 (alpha)
  • Rat(24170) adducin 1 (alpha)
  • Zebrafish(555511) adducin 1 (alpha)
  • naked mole-rat(101699444) adducin 1 (alpha)
  • domestic guinea pig(100713878) adducin 1 (alpha)
  • sheep(101123212) adducin 1 (alpha)
  • cow(507193) adducin 1 (alpha)
  • Horse(100051451) adducin 1 (alpha)
  • domestic cat(101097481) adducin 1 (alpha)
  • dog(488796) adducin 1 (alpha)
  • chicken(422882) adducin 1 (alpha)

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ADD1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-ADD1 (pSer726) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ADD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ADD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Add1,
Species
mouse
MISSION® esiRNA, targeting human ADD1,
Species
human