5.05417

Oxymetazoline Hydrochloride

• Synonym(s): Oxymetazoline Hydrochloride, 6-(tert-butyl)-3-((4,5-dihydro-1H-imidazol-2-yl)methyl)-2,4-dimethylphenol hydrochloride, 3-[(4,5-Dihydro-1H-imidazol-2-yl)me­thyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride, Alpha 2 Adrenergic Receptor Agonist, Oxymetazoline hydrochlo
• Empirical Formula (Hill Notation): C₁₆H₂₄N₂O · xHCl
• CAS Number: 2315-02-8
• Molecular Weight: 260.37 (free base basis)
• MDL number: MFCD00058147
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥99% (HPLC)
• Quality Level: 100
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: white
• solubility: water: 50 mg/mL
• storage temp.: 2-8°C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI key: BEEDODBODQVSIM-UHFFFAOYSA-N

Description

General description

α₂-Adrenergic receptor agonist. Exhibits over 60-fold greater selectivity for α_2A receptors over α_2β receptors. Enhances EGF- and PDGF-induced DNA synthesis.

Biochem/physiol Actions

Primary Target
α₂ adrenergic

Warning

Toxicity: Toxic (F)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Makara, G.B., et al. 1995. Eur. J. Pharmacol.287, 43.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H330 - H318 - H412
• Precautionary Statements: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Storage Class Code: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3