Skip to Content
Merck
All Photos(1)

Documents

860491P

Avanti

D-ribo-Phytosphingosine-1-Phosphate

Avanti Research™ - A Croda Brand 860491P, powder

Synonym(s):

4-hydroxysphinganine-1-phosphate (Saccharomyces Cerevisiae)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C18H40NO6P
CAS Number:
383908-62-1
Molecular Weight:
397.49
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 mg (860491P-1mg)
pkg of 1 × 5 mg (860491P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860491P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C18H40NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)18(21)16(19)15-25-26(22,23)24/h16-18,20-21H,2-15,19H2,1H3,(H2,22,23,24)/t16-,17+,18-/m0/s1

InChI key

AYGOSKULTISFCW-KSZLIROESA-N

General description

D-ribo-Phytosphingosine-1-Phosphate (phS1P) is a ligand for the sphingosine-1-phosphate receptor 4. It is present in the membrane of plants, fungi, mammalian tissues and bacteria.

Application

D-ribo-Phytosphingosine-1-Phosphate is suitable for use as a ligand for sphingosine-1-phosphate receptor 4 in competition binding studies. It is also suitable for use as an internal standard for the quantification of spingoid bases in maize samples using mass spectrometry and reverse phase high-performance liquid chromatography

Biochem/physiol Actions

D-ribo-Phytosphingosine-1-Phosphate (phS1P) plays a key role in cell growth. In yeast, it coordinates response to heat stress.

Packaging

5 mL Amber Glass Screw Cap Vial (860491P-1mg)
5 mL Amber Glass Screw Cap Vial (860491P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Maize seedling blight induced by Fusarium verticillioides: Accumulation of fumonisin B1 in leaves without colonization of the leaves
Baldwin TT, et al.
Journal of Agricultural and Food Chemistry, 62(9), 2118-2125 (2014)
Translocation of sphingoid bases and their 1-phosphates, but not fumonisins, from roots to aerial tissues of maize seedlings watered with fumonisins
Zitomer NC, et al.
Journal of Agricultural and Food Chemistry, 58(12), 7476-7481 (2010)
Pharmacological characterization of human S1P4 using a novel radioligand,[4, 5-3H]-dihydrosphingosine-1-phosphate
Fossetta J, et al.
British Journal of Pharmacology, 142(5), 851-860 (2004)
Asymmetric synthesis of d-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy) acetaldehyde
Liu Z, et al.
The Journal of Organic Chemistry, 75(13), 4356-4364 (2010)
Priya Gupta et al.
Plant molecular biology, 103(1-2), 173-184 (2020-02-27)
Arabidopsis LONG-CHAIN BASE KINASE 1 (LCBK1) interacts with MEDEA, a component of PCR2 complex that negatively regulates immunity. LCBK1 phosphorylates phytosphingosine and thereby promotes stomatal immunity against bacterial pathogens. Arabidopsis polycomb-group repressor complex2 (PRC2) protein MEDEA (MEA) suppresses both pattern-triggered

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service