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927856

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, azide functionalized, 1ml, OD 50, In in water

Synonym(s):

AuNP, GdNP, Gold NP

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.23

Quality Level

description

Azide surface density: 1/nm2

concentration

In in water

OD

50

core diam.

10 nm , Coefficient of variance <12%

diameter

10 nm

λmax

520 nm

PDI

<0.200

functional group

azide

storage temp.

2-8°C

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Azide functionalized gold nanoparticles are suitable for covalent conjugation of any molecule with a terminal alkyne through click chemistry. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.

Azide functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Storage and Stability

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Recent applications of click chemistry for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles
Poonthiyil, Vivek, et al
Beilstein Journal of Organic Chemistry, 14.1, 11-24 (2018)
Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles
Brennan, Jennifer L., et al
Bioconjugate Chemistry, 17.6, 1373-1375 (2006)
Chain-like assembly of gold nanoparticles on artificial DNA templates via `click chemistry?
Fischler, Monika, et al
Chemical Communications (Cambridge, England), 2, 169-171 (2008)

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