EZGLP2

Rat/Human GLP-2 ELISA Kit

detects GLP-2 in 50 μL serum, plasma or cell culture supernatent

• Synonym(s): Glucagon-like peptide-2
• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.32

Properties

• product name: GLP-2 ELISA, This GLP-2 ELISA is used to measure & quantify GLP-2 levels in Metabolism & Endocrine research.
• Quality Level: 200
• species reactivity: human, rat
• packaging: kit of 1 × 96 wells
• parameter: 50 μL sample volume (4hr assay)
• assay range: accuracy: 75-97%; (Human); accuracy: 94-109%; (Rat); sensitivity: 1 ng/mL; (50 μl sample size); standard curve range: 1-64 ng/mL; inter-assay cv: <12%; intra-assay cv: <10%
• technique(s): ELISA: suitable
• input: sample type plasma (K2 EDTA); sample type serum
• application(s): research use
• detection method: colorimetric (450nm/590nm)
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

The glucagon-like peptides GLP-1 and GLP-2 are important gut hormones released from the small intestine upon nutrient ingestion. In circulation, GLP-2 is present in two molecular forms, GLP-2 (1-33) and GLP-2 (3-33). Similar to GLP-1, active form GLP-2 (1-33) is cleaved to inactive form GLP-2 (3-33) by protease DPPIV. GLP-2 has been shown to play important roles in the regulation of gastrointestinal functions (digestion, absorption, motility, epithelial growth, and blood flow) and bone resorption. Thus, GLP-2 or its analogs may have therapeutic potentials for the treatment of diseases such as Crohn’s disease and osteoporosis.

Specificity

Human GLP-2 1-33 100%
Human GLP-2 3-33 112%
Rat GLP-2 101%

Application

Research Category
Metabolism

Research Sub Category
Osteoporosis

This assay requires 50 µl of rat or human samples and is performed at room temperature as a 4 hour assay. GLP-2 has also been detected in guinea pig, horse, porcine, and non-human primate samples.

Used to detect/quantify: GLP-2

Other Notes

Please contact Technical Service for linearity of dilution.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Safety Information

• Pictograms: GHS06,GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H290,H302 + H332,H311,H317,H319,H335,H411
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects