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F-002

Supelco

Fentanyl solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C22H28N2O
CAS Number:
437-38-7
Molecular Weight:
336.47
MDL number:
MFCD00661055
UNSPSC Code:
41116107
PubChem Substance ID:
329799618
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3

InChI

1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3

InChI key

PJMPHNIQZUBGLI-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

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General description

A potent synthetic narcotic analgesic and local anesthetic with a rapid onset and short duration of action. Sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®, fentanyl is more potent than morphine in analgesic activity. This certified solution standard is suitable for a variety of LC/MS or GC/MS testing applications from forensic analysis, clinical toxicology, and pain prescription monitoring to urine drug testing and pharmaceutical research.

Application


  • Analgesic potency assay: Fentanyl is widely used in analgesic potency assays due to its strong opioid receptor agonist properties, providing a benchmark for evaluating the efficacy of new analgesics in preclinical and clinical settings (Chakravartula et al., 2024).

  • In vitro pharmacology studies: As a high-purity fentanyl analytical standard, it is crucial for in vitro pharmacology studies to understand the drug′s interaction with opioid receptors and its effects on neural pathways (Kanashiro et al., 2024).

  • Pharmacological research chemical supply: Fentanyl citrate solution serves as a valuable resource in pharmacological research, particularly in studies focusing on pain management and opioid addiction therapies (Lee et al., 2024).

  • Synthetic opioid solution: This synthetic opioid is utilized in scientific studies to explore safer and more effective pain relief methods, such as patient-controlled analgesia systems (Huang et al., 2024).

  • Opioid receptor agonist research: Fentanyl is employed to study opioid receptor dynamics, aiding in the development of targeted therapies for pain and opioid use disorders (Song et al., 2024).

Legal Information

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Carfentanil-D5 Oxalate solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

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Norcarfentanil oxalate oxalate salt solution, 100 μg/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL, Cerilliant®

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Valeryl fentanyl hydrochloride solution, 100 μg/mL in methanol (as a free base), certified reference material, ampule of 0.5 mL, Cerilliant®

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Acryl fentanyl hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

O-047

Ocfentanil solution, 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®

F-048

p-Fluorobutyryl fentanyl (PFBF) solution, 100 μg/mL in methanol (), certified reference material, ampule of 0.5 mL, Cerilliant®

H-130

(±)-β-Hydroxythiofentanyl hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

D-168

N-Desmethyl U-47700-D3 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

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N-Desmethyl U-47700 solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

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4-Fluoro-isobutyryl fentanyl solution, 100 μg/mL in methanol, certified reference material, ampule of 0.5 mL, Cerilliant®

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Methoxyacetyl fentanyl hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

V-068

Valeryl fentanyl-D5 hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

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Acryl fentanyl-D5 hydrochloride solution, 100 μg/mL in methanol (as free base), certified reference material, ampule of 0.5 mL, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Esther Encinas et al.
Paediatric drugs, 15(3), 247-257 (2013-05-10)
Fentanyl is a synthetic opioid commonly used as an anesthetic and also increasingly popular as a sedative agent in neonates. Initial dosage regimens in this population are often empirically derived from adults on a body weight basis. However, ontogenic maturation
[Pain therapy. Treating pain patients with opioid preparations].
MMW Fortschritte der Medizin, 155(6), 70-71 (2013-05-25)
Nele Plock et al.
International journal of clinical pharmacology and therapeutics, 51(6), 495-508 (2013-04-25)
Intranasal Fentanyl Spray (INFS) was developed for the treatment of breakthrough pain (BTP) in cancer patients using a new route of administration. Dose strengths of 50, 100, and 200 μg INFS (Instanyl®) are currently on the market, however, some adult
An EMS guide to chronic pain.
Kevin T Collopy et al.
EMS world, 42(7), 59-63 (2013-08-10)
Elzbieta P Wala et al.
Journal of opioid management, 9(2), 85-96 (2013-05-28)
Opioids may cause progressive enhancement of pain sensitivity (opioid-induced hyperalgesia [OIH]) and thus, exacerbate existing pain. Animal studies also demonstrate paradoxical OIH with an ultralow dose (ULD, subanalgesic) of opioid; eg, the μ-opioid, morphine. Repeated administration of ULD-morphine resulted in
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