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850402C

Avanti

4ME 16:0 PE

1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine, chloroform

Synonym(s):

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphoethanolamine; PE(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))

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About This Item

Empirical Formula (Hill Notation):
C45H90NO8P
CAS Number:
201036-16-0
Molecular Weight:
804.17
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850402C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850402C

concentration

10 mg/mL (850402C-25mg)

lipid type

omega FAs

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O

Application

4ME 16:0 PE is suitable for use in the preparation of Vaxfectin, a plasmid DNA vaccine. It may also be used in the oriented circular dichroism (OCD) experiment for the measurement of peptide orientation in lipid bilayers.

Packaging

5 mL Clear Glass Sealed Ampule (850402C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores
Hermanson G, et al.
Proceedings of the National Academy of Sciences of the USA, 101(37), 13601-13606 (2004)
Multiple states of beta-sheet peptide protegrin in lipid bilayers
Heller WT, et al.
Biochemistry, 37(49), 17331-17338 (1998)
Many-body effect of antimicrobial peptides: on the correlation between lipid?s spontaneous curvature and pore formation
Lee MT, et al.
Biophysical Journal, 89(6), 4006-4016 (2005)
Jianjun Pan et al.
The journal of physical chemistry. B, 116(51), 14829-14838 (2012-12-04)
Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their interactions are crucial in ether lipid mediated cholesterol trafficking. We report on cholesterol's molecular interactions with ether lipids as determined using a combination of small-angle neutron and X-ray

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