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245070

Sigma-Aldrich

Tetramethylammonium acetate

≥97%

Synonym(s):

N,N,N-trimethyl-methanaminium acetate

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About This Item

Linear Formula:
(CH3)4N(OCOCH3)
CAS Number:
10581-12-1
Molecular Weight:
133.19
Beilstein:
3571830
EC Number:
234-179-3
MDL number:
MFCD00011630
UNSPSC Code:
12352116
PubChem Substance ID:
24854730
NACRES:
NA.22

Assay

≥97%

form

solid

mp

184 °C (dec.) (lit.)

SMILES string

CC([O-])=O.C[N+](C)(C)C

InChI

1S/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;/p-1

InChI key

MRYQZMHVZZSQRT-UHFFFAOYSA-M

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mesude Bicak et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(26), 15172-15181 (2020-06-14)
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options
Daniel L J Thorek et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(2), 881-891 (2018-09-27)
The impact of androgen receptor (AR) activity in breast cancer biology is unclear. We characterized and tested a novel therapy to an AR-governed target in breast cancer.Experimental Design: We evaluated the expression of prototypical AR gene products human kallikrein 2
Aleksandra M Urbanska et al.
Cancer biotherapy & radiopharmaceuticals, 35(6), 459-473 (2020-02-06)
An α particle-emitting nanodrug that is a potent and specific antitumor agent and also prompts significant remodeling of local immunity in the tumor microenvironment (TME) has been developed and may impact the treatment of melanoma. Biocompatible ultrasmall fluorescent core-shell silica
Zhiyuan Zhao et al.
ACS omega, 5(30), 19247-19254 (2020-08-11)
In this work, poly(ethylene terephthalate) (PET) chain-extending products with different molecular weights were prepared by reactive extrusion using isocyanate trimer (C-HK) as the trifunctional chain extender. The effect of the chain extender C-HK on the intrinsic viscosity, melt flow property
Alexey A Nazarov et al.
Dalton transactions (Cambridge, England : 2003), 44(8), 3614-3623 (2014-11-20)
Chemotherapeutics for the treatment of tumorigenic conditions that feature novel modes of action are highly sought after to overcome the limitations of current chemotherapies. Herein, we report the conjugation of the alkylating agent chlorambucil to the RAPTA scaffold, a well-established

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