430722
(R)-3-Pyrrolidinol hydrochloride
98%
Synonym(s):
(R)-3-Hydroxypyrrolidine hydrochloride
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About This Item
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Assay
98%
form
solid
optical activity
[α]20/D −7.6°, c = 3.5 in methanol
mp
104-107 °C (lit.)
functional group
hydroxyl
SMILES string
Cl.O[C@@H]1CCNC1
InChI
1S/C4H9NO.ClH/c6-4-1-2-5-3-4;/h4-6H,1-3H2;1H/t4-;/m1./s1
InChI key
QPMSJEFZULFYTB-PGMHMLKASA-N
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Application
(R)-3-Pyrrolidinol hydrochloride can be used as a building block to synthesize:
- Biaryl carboxamide functional groups containing bis-aminopyrrolidine ureas as potential antagonists of the melanin-concentrating hormone receptor-1.
- Pyrrolidinol based ionic liquids.
- Optically active 2-tritylpyrrolidine based organocatalysts.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Commercially available salts as building blocks for new ionic liquids
ACS Symposium Series, 15(14), 3439-3445 (2003)
A Recyclable Chiral 2-(Triphenylmethyl) pyrrolidine Organocatalyst Anchored to [60] Fullerene
advanced synthesis and catalysis, 361(12), 2936-2944 (2019)
Synthesis and structure-activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)
Bioorganic & medicinal chemistry letters, 15(14), 3439-3445 (2005)
A Recyclable Chiral 2-(Triphenylmethyl) pyrrolidine Organocatalyst Anchored to [60] Fullerene
Advanced Synthesis & Catalysis, 361(12), 2936-2944 (2019)
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