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  • Asymmetric hydrogenation of ketones catalyzed by a ruthenium(II)-indan-ambox complex.

Asymmetric hydrogenation of ketones catalyzed by a ruthenium(II)-indan-ambox complex.

Chemical communications (Cambridge, England) (2010-04-22)
Wei Li, Guohua Hou, Chunjiang Wang, Yutong Jiang, Xumu Zhang
ABSTRACT

(S,R)-Indan-ambox ligand and its ruthenium(II) complex have been prepared and successfully applied to asymmetric hydrogenation of prochiral simple ketones. A wide range of unfunctionalized ketones are reduced by Ru(II)-indan-ambox catalyst with excellent enantioselectivities (up to 97% ee).

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Indan, 95%
Supelco
Indan, analytical standard