- Concise total synthesis of (+/-)-aspidospermidine via an oxidative Hosomi-Sakurai process.
Concise total synthesis of (+/-)-aspidospermidine via an oxidative Hosomi-Sakurai process.
Chemical communications (Cambridge, England) (2009-05-14)
Cyrille Sabot, Kimiaka C Guérard, Sylvain Canesi
PMID19436917
ABSTRACT
A concise total synthesis of (+/-)-aspidospermidine has been achieved in twelve steps from inexpensive 4-ethylphenol, based on an oxidative Hosomi-Sakurai reaction via the concept of "aromatic ring umpolung".