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A0156

Sigma-Aldrich

N-(4-Aminobutyl)-N-ethylisoluminol

≥90%, powder

Synonym(s):

4-(N1-Ethyl-4-aminobutylamino)phthalic hydrazide, 6-[N-(4-Aminobutyl)-N-ethylamino]-2,3-dihydro-1,4-phthalazinedione, ABEI

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About This Item

Empirical Formula (Hill Notation):
C14H20N4O2
CAS Number:
66612-29-1
Molecular Weight:
276.33
Beilstein:
920895
MDL number:
MFCD00010559
UNSPSC Code:
12352204
PubChem Substance ID:
24890404
NACRES:
NA.83

product name

N-(4-Aminobutyl)-N-ethylisoluminol, ≥90%

Assay

≥90%

form

powder

mp

259-260 °C (lit.)

solubility

glacial acetic acid: 50 mg/mL, clear, colorless to yellow

storage temp.

2-8°C

SMILES string

CCN(CCCCN)c1ccc2C(=O)NNC(=O)c2c1

InChI

1S/C14H20N4O2/c1-2-18(8-4-3-7-15)10-5-6-11-12(9-10)14(20)17-16-13(11)19/h5-6,9H,2-4,7-8,15H2,1H3,(H,16,19)(H,17,20)

InChI key

LEOJISUPFSWNMA-UHFFFAOYSA-N

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Features and Benefits

Efficient chemiluminescent NH2-coupling reagent for detection of a wide variety of proteins down to the picomole range.

Other Notes

Reportedly, the use of this material in chemiluminescent assays has distinct advantages over conventional radioimmunoassay.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ying Chai et al.
Analytica chimica acta, 715, 86-92 (2012-01-17)
An electrochemiluminescence (ECL) biosensor for simultaneous detection of adenosine and thrombin in one sample based on bifunctional aptamer and N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanoparticles (ABEI-AuNPs) was developed. A streptavidin coated gold nanoparticles modified electrode was utilized to immobilize biotinylated bifunctional aptamer
Dayong Tian et al.
Chemical communications (Cambridge, England), 47(17), 4959-4961 (2011-03-25)
A novel strategy for the synthesis of CF-AuNMs by reducing HAuCl(4) with ABEI in aqueous solution at room temperature is reported. No additional stabilizing and reducing reagents are needed, and various morphologies of CF-AuNMs can be obtained. It could be
F Kohen et al.
Steroids, 38(1), 73-88 (1981-07-01)
A solid-phase immunoassay procedure for the determination of progesterone in human plasma is described, which utilizes chemiluminescence as the end-point. A progesterone-isoluminol conjugate serves as the chemiluminescent marker. An IgG fraction of antiserum to progesterone-11 alpha-hemisuccinate bovine serum albumin is
Zian Lin et al.
Journal of chromatography. A, 1170(1-2), 118-121 (2007-10-02)
A simple and convenient end-column chemiluminescence (CL) detection coupled to pressurized capillary electrochromatography (pCEC) was described. Luminol and N-(4-aminobutyl)-N-ethylisoluminol (ABEI) were adopted as mode compounds to evaluate the feasibility of end-column reactor. Detailed analysis of ABEI revealed that the high
M-L Calvo-Muñoz et al.
Bioelectrochemistry (Amsterdam, Netherlands), 66(1-2), 139-143 (2005-04-19)
The electrochemiluminescence (ECL) of a luminol derivate (ABEI) generated both by a carbon electrode and a polypyrrole-coated carbon electrode was examined. It was found that the polypyrrole film (ppy) did not inhibit the ECL. After that, ABEI anchored on a
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