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Key Documents

08569

Sigma-Aldrich

2-Amino-2-methyl-1,3-propanediol

BioUltra, ≥99.5% (NT)

Synonym(s):

AMPD, Ammediol

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About This Item

Linear Formula:
(HOCH2)2C(NH2)CH3
CAS Number:
Molecular Weight:
105.14
Beilstein:
635708
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

vapor density

3.63 (vs air)

Quality Level

vapor pressure

~10 mmHg ( 152 °C)

product line

BioUltra

Assay

≥99.5% (NT)

form

crystalline

impurities

insoluble matter, passes filter test

pH

10.5-11.5 (25 °C, 1 M in H2O)

useful pH range

7.8-9.7

pKa (25 °C)

8.8

bp

151 °C/10 mmHg (lit.)

mp

100-110 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

carbonate (CO32-): ≤1000 mg/kg
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.03

SMILES string

CC(N)(CO)CO

InChI

1S/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3

InChI key

UXFQFBNBSPQBJW-UHFFFAOYSA-N

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Application

2-Amino-2-methyl-1,3-propanediol can be used to study biological buffers. 2-Amino-2-methyl-1,3-propanediol has been used in a study to afford a new family of isostructural octanuclear Cu4Ln4 complexes. 2-Amino-2-methyl-1,3-propanediol has also been used in a study to improve cooling refrigerants for low-temperature applications.
Buffer component in a SDS-gradient gel electrophoresis system that separates polypeptides in the molecular weight range of 1500 to 100,000. Used as a spacer in isotachophoresis of proteins. Also used as a buffer for the determination of alkaline phosphatase activity.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

>212.0 °F

Flash Point(C)

> 100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S Canepari et al.
Talanta, 44(11), 2059-2067 (2008-10-31)
Formation constants of the silver(I) complexes with some amino-alcohols have been determined at 25 degrees C in 0.5 M KNO(3) by means of two independent potentiometric measurements employing glass and silver electrode. The ligands considered are: sec-butylamine, 2-amino-1-propanol, 2-amino-1-methoxy-propane, 2-amino-2-methyl-1-propanol
A new family of octanuclear Cu4Ln4 (Ln = Gd, Tb and Dy) spin clusters
Alley, K.G., et al.
Dalton Transactions, 7, 59-63 (2008)
Jung-Yeon Park et al.
Environmental science & technology, 37(8), 1670-1675 (2003-05-07)
Acid gas absorption technology is of great importance in these days for the prevention of global warming and the resulting worldwide climate change. More efficient process design and development for the removal of acid gases has become important, together with
Karen M O'Connor et al.
Journal of pharmaceutical sciences, 91(10), 2271-2281 (2002-09-13)
Dissolution of diclofenac from compressed discs containing mixtures of a diclofenac salt and a basic excipient, in various w/w ratios, was examined. Two diclofenac salts, diclofenac deanol (DDNL) and diclofenac tert-butylamine, and the basic excipient 2-amino-2-methyl-1,3-propanediol (AMPD) were examined. Inclusion
H Kikuchi et al.
The Tohoku journal of experimental medicine, 173(4), 391-397 (1994-08-01)
The method by MacQueen and Plaut was modified to devise simple microdetermination method of l-lactate which is applicable to deproteinized blood sample. Blood was deproteinized with addition of 25% (w/w) trichloroacetic acid (TCA), and 0.075 M 2-amino-2-methyl-1, 3-propanediole (AMPD) was

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