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317306

Sigma-Aldrich

3,3′-Iminodipropionitrile

technical grade, 90%

Synonym(s):

Bis(2-cyanoethyl)amine

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About This Item

Linear Formula:
HN(CH2CH2CN)2
CAS Number:
Molecular Weight:
123.16
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Assay

90%

form

liquid

refractive index

n20/D 1.47 (lit.)

bp

205 °C/25 mmHg (lit.)

density

1.02 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

N#CCCNCCC#N

InChI

1S/C6H9N3/c7-3-1-5-9-6-2-4-8/h9H,1-2,5-6H2

InChI key

SBAJRGRUGUQKAF-UHFFFAOYSA-N

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile.
Jordi Llorens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 110(1), 244-245 (2009-05-01)
Henrik A Hartmann
Neurotoxicology, 26(2), 277-283 (2005-02-17)
Iminodipropionitrile (IDPN) was given to rats on diets with normal copper levels, 5 ppm, and to rats on diets with high copper levels, 100 ppm. The former developed neurological symptoms, namely choreoathetoid head movements, circling and retropulsion, while the latter
Ana Seoane et al.
Acta neuropathologica, 106(5), 458-470 (2003-08-05)
3,3'-Iminodipropionitrile (IDPN) is a neurotoxic compound that causes both a proximal neurofilamentous axonopathy and loss of the vestibular sensory hair cells. We used immunocytochemistry to examine changes in the expression of heavy, medium and light neurofilament (NF-H, NF-M, NF-L) proteins
Takeshi Tanaka et al.
The Journal of toxicological sciences, 44(2), 93-105 (2019-02-07)
Maternal exposure to 3,3'-iminodipropionitrile (IDPN) affects hippocampal neurogenesis in mouse offspring, with biphasic disruption, which facilitates neurogenesis during exposure and reduces the broad range of the granule cell lineage population at the adult stage. The present study investigated the epigenetically
Haseeb Ahmad Khan
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 64(7-8), 791-796 (2011-03-11)
Exposure of iminodipropionitrile (IDPN) to rodents produces permanent behavioral syndrome characterized by repetitive head movements, circling and back walking. Other synthetic nitriles of industrial importance such as crotonitrile and allylnitrile are also able to produce similar motor deficits in experimental

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