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The molybdenum cofactor.

The molybdenum cofactor.

The Journal of biological chemistry (2013-03-30)

Ralf R Mendel

ABSTRACT

The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase. The biosynthesis of Moco involves the complex interaction of six proteins and is a process of four steps, which also require iron, ATP, and copper. After its synthesis, Moco is distributed, involving Moco-binding proteins. A deficiency in the biosynthesis of Moco has lethal consequences for the respective organisms.

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

Molybdenum, powder, 10 μm, ≥99.95% trace metals basis

Sigma-Aldrich

Molybdenum, powder, <150 μm, 99.9% trace metals basis

Sigma-Aldrich

Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis

Sigma-Aldrich

Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis

Sigma-Aldrich

Molybdenum, nanopowder, <100 nm particle size (TEM), 99.8% trace metals basis

Sigma-Aldrich

Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis

Sigma-Aldrich

Molybdenum, powder, 1-5 μm, ≥99.9% trace metals basis

Sigma-Aldrich

Molybdenum, powder, <150 μm, 99.99% trace metals basis

Molybdenum, rod, 200mm, diameter 10.0mm, centerless ground, 99.9%

Molybdenum, foil, 25mm disks, thickness 0.025mm, annealed, 99.9%

Molybdenum, foil, 50mm disks, thickness 0.01mm, 99.9%

Molybdenum, foil, 50mm disks, thickness 0.30mm, annealed, 99.9%

Molybdenum, foil, 4mm disks, thickness 0.125mm, annealed, 99.9%

Molybdenum, foil, 1m coil, thickness 0.025mm, annealed, 99.9%

Molybdenum, foil, 6mm disks, thickness 0.015mm, annealed, 99.9%

Molybdenum, foil, 50mm disks, thickness 0.008mm, 99.9%

Molybdenum, foil, 6mm disks, thickness 0.15mm, annealed, 99.9%

Molybdenum, foil, 4mm disks, thickness 0.15mm, annealed, 99.9%

Molybdenum, foil, 5m coil, thickness 0.04mm, coil width 0.7mm, annealed, 99.9%

Molybdenum, rod, 500mm, diameter 15.0mm, centerless ground, 99.9%

Molybdenum, foil, 8mm disks, thickness 0.075mm, annealed, 99.9%

Molybdenum, foil, 8mm disks, thickness 0.01mm, 99.9%

Molybdenum, foil, 8mm disks, thickness 0.005mm, 99.9%

Molybdenum, foil, 8mm disks, thickness 0.020mm, annealed, 99.9%

Molybdenum, foil, light tested, 100x100mm, thickness 0.01mm, 99.9%

Molybdenum, foil, 8mm disks, thickness 0.015mm, as rolled, 99.9%

Molybdenum, foil, 6mm disks, thickness 0.5mm, annealed, 99.9%

Molybdenum, foil, light tested, 130x130mm, thickness 0.015mm, as rolled, 99.9%

Molybdenum, wire reel, 1m, diameter 1.0mm, annealed, 99.95%

Molybdenum, wire reel, 5m, diameter 0.025mm, hard, 99.95%