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Key Documents

SML2736

Sigma-Aldrich

NPBA

≥98% (HPLC)

Synonym(s):

N-(2-((4-nitro-2-(trifluoromethyl)phenyl)amino)ethyl)benzamide

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About This Item

Empirical Formula (Hill Notation):
C16H14F3N3O3
CAS Number:
Molecular Weight:
353.30
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

NPBA is a potent and selective agonist (activator) of potassium K2P channel TASK-3 (KCNK9).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Fuyun Tian et al.
Molecular pharmacology, 96(1), 26-35 (2019-04-25)
The TASK-3 channel is a member of the K2P family that is important for the maintenance of the resting membrane potential. Previous studies have demonstrated that the TASK-3 channel is involved in several physiologic and pathologic processes, including sleep/wake control

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