M3935
Meloxicam sodium salt hydrate
≥98% (HPLC)
Synonym(s):
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate, Metacam sodium salt hydrate, Mobec sodium salt hydrate, UH-AC 62XX sodium salt hydrate
About This Item
Assay
≥98% (HPLC)
form
powder
color
light yellow to dark yellow
solubility
DMSO: 5 mg/mL, clear
originator
Boehringer Ingelheim
storage temp.
room temp
SMILES string
O.[Na+].CN1C(C(=O)Nc2ncc(C)s2)=C([O-])c3ccccc3S1(=O)=O
InChI
1S/C14H13N3O4S2.Na.H2O/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2;;/h3-7,18H,1-2H3,(H,15,16,19);;1H2/q;+1;/p-1
InChI key
IZBZAOZGNNQKPJ-UHFFFAOYSA-M
Gene Information
human ... PTGS2(5743)
Application
- as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumor
- as an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vultures
- as a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)
- to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells
Biochem/physiol Actions
Features and Benefits
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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