- A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.
A novel heterocyclic atom exchange reaction with Lawesson's reagent: a one-pot synthesis of dithiomaltol.
Chemical communications (Cambridge, England) (2005-12-24)
Daniel Brayton, Faith E Jacobsen, Seth M Cohen, Patrick J Farmer
PMID16372107
ABSTRACT
A one-pot reaction of maltol with Lawesson's reagent generates dithiomaltol, a thiopyran-4-thione, via an unusual heterocyclic atom exchange (HCAE) reaction; only pyrones with proton or aliphatic substituents undergo the HCAE substitution.
MATERIALS