Skip to Content
MilliporeSigma
HomeProductsAnalytical ChemistryReference MaterialsCertified Reference Materials

Certified Reference Materials

A collection of various chemical bottles and containers with different sizes, shapes, and colors. Some bottles have red caps and labels with hazard symbols indicating flammable and corrosive substances. There are also small vials with yellow liquid, alongside tubes with white caps.

We offer a wide range of Certified Reference Materials (CRMs) for testing applications including forensic and clinical toxicology analysis, diagnostic testing, therapeutic drug monitoring, Cannabis testing, environmental analysis, pharmaceutical research, and food & beverage testing.

Our Supelco® family of CRMs are manufactured and tested under ISO 17034 and ISO/IEC 17025 double accreditation, the highest quality system achievement for reference material producers. We also distribute CRMs from internationally recognized producers such as Cerilliant, IRMM, Paragon Scientific and Whitehouse Scientific. 

Our products include:

  • Organic and inorganic CRMs for chromatography, mass spectrometry, quantitative NMR, ICP, and AAS testing platforms. 
  • Environmental matrix CRMs for testing parameters such as alkalinity, BOD, pH calibration, turbidity, and soil QC.
  • CRMs for applications including industrial raw materials, spectroscopy, air monitoring, clinical chemistry, physical properties, and food & agriculture testing.

Related Product Resources

Related Product Categories
Pharmacopeia & Metrological Institute Standards
Explore a wide range of quality control standards from USP, EP, BAM, NIST, and more for pharma labs.
Physical & Chemical Property Standards
Certified reference materials (CRMs) offer reliable calibration standards for equipment across various analytical applications.
Food & Cosmetic Component Standards
Discover diverse analytical standards and CRMs for food, cosmetics, fragrances, UV-blockers, sweeteners, essential oils, toxins, and more.
Matrix Materials Standards
We offer a broad range of matrix certified reference materials for drinking water, soil, food, wastewater and environmental testing.
ICP & AAS standards
Enhance inorganic trace analysis with our certified AAS and ICP standards. NIST-traceable solutions available.
Ion Chromatography Standards
Our selection of reference standards for ion chromatography includes certified reference material (CRMs) solutions of single- and multi- ions and carbohydrates for the accurate analysis.
Chromatography Standards
Certified Reference Materials & reference standards for chromatography-based testing applications including forensic and clinical toxicology analysis, diagnostic testing, therapeutic drug monitoring, cannabis testing, environmental analysis, pharmaceutical research, and food & beverage testing.
Related Applications
Gas Chromatography (GC)
Gas chromatography separates volatile compounds in the gas phase, applied in various industries for quality control.
Liquid Chromatography at Low Pressures
Low pressure liquid chromatography (LPLC) is a chromatographic technique that operates at low pressures to drive the mobile phase onto the column containing a stationary phase by the action of a pump.
Mass Spectrometry
Mass spectrometry (MS) is an analytical tool used to identify compounds, determine chemical structure, and assess isotopic abundance. In MS, samples are ionized, and the resulting ions are identified based on their mass-to-charge (m/z) ratios.
Photometry & Reflectometry
Photometry measures light absorption for analyte quantification, while reflectometry determines surface characteristics like color.
Nuclear Magnetic Resonance (NMR)
NMR spectroscopy elucidates molecular structure and purity via nuclear spin states in a strong magnetic field.
Atomic Spectroscopy Overview
Atomic spectroscopy uses the energy absorbed or emitted by electrons to identify and quantify the elemental composition of a sample. It includes various analytical techniques, such as AAS, AES, FAA, GFAA, ICP-OES, ICP-MS and XRF.
Titration & Karl Fischer Analysis
Karl Fischer titration determines water content in raw materials and products, a widely used analytical method.
Calibration, Qualification & Validation
Reference materials selection is vital for accurate testing, supporting method validation, calibration, and measurement uncertainty assessment.
Related Services
Custom Reference Materials
Browse for high-quality Custom Reference Materials tailored to your specific analytical applications from Supelco. Get your quote now!
Calibration & Verification
Microbiological testing services ensure reliable test results, critical for maintaining confidence in test equipment and performance.
Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?