1612619

N-Acetylneuraminic acid

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): N-Acetylneuraminic acid dihydrate, o-Sialic acid
• Empirical Formula (Hill Notation): C₁₁H₁₉NO₉ · 2H₂O
• CAS Number: 131-48-6
• Molecular Weight: 345.30
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: n-acetylneuraminic acid
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: -65 to -96°C
• InChI: 1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1
• InChI key: SQVRNKJHWKZAKO-PFQGKNLYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
N-Acetylneuraminic Acid is a commonly determined monosaccharide formed as a degradation product of therapeutic glycoproteins.

Application

N-Acetylneuraminic acid USP reference standard for use in specified quality tests and assays.

Also used to prepare standard stock solution during oligosaccharide and sialic acid analysis according to the given general chapters of United States Pharmacopeia (USP):

• 〈210〉 Monosaccharide analysis
• 〈129〉 Analytical procedures for recombinant therapeutic monoclonal antibodies

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

This product is part of the USP Biologics program.

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable