PHL89612

Cryptotanshinone

phyproof^® Reference Substance

• Synonym(s): (R)-(−)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione, Tanshinone C
• Empirical Formula (Hill Notation): C₁₉H₂₀O₃
• CAS Number: 35825-57-1
• Molecular Weight: 296.36
• Beilstein: 5445400
• MDL number: MFCD07636810
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥90.0% (HPLC)
• form: solid
• manufacturer/tradename: PhytoLab
• SMILES string: C[C@H]1COC2=C1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23
• InChI: 1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
• InChI key: GVKKJJOMQCNPGB-JTQLQIEISA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation and to inhibit macrophage migration negatively regulate the PI3K pathway. It has demonstrated activity against several strains of Staphylococcus aureus.

Other Notes

This compound is commonly found in plants of the genus: salvia

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable