M1555
MAHMA NONOate
Synonym(s):
6-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-hexanamine, NOC-9
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About This Item
Empirical Formula (Hill Notation):
C8H20N4O2
CAS Number:
Molecular Weight:
204.27
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
shipped in
dry ice
storage temp.
−70°C
SMILES string
[H][N+]([H])(C)CCCCCCN(C)N([O-])N=O
InChI
1S/C8H19N4O2/c1-9-7-5-3-4-6-8-11(2)12(14)10-13/h9H,3-8H2,1-2H3/q-1/p+1
InChI key
WASRCWNCCFPNEJ-UHFFFAOYSA-O
Application
NO donor
Biochem/physiol Actions
NO release: t1/2 = 3 min (phosphate buffer at 22° C)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Stefan Muenster et al.
Anesthesiology, 125(5), 952-963 (2016-10-19)
Transfusion of packed erythrocytes stored for a long duration is associated with increased pulmonary arterial pressure and vascular resistance. Prolonged storage decreases erythrocyte deformability, and older erythrocytes are rapidly removed from the circulation after transfusion. The authors studied whether treating
S H Lin et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 20(9), 1380-1391 (2000-09-20)
Neuronal injury may be dependent upon the generation of the free radical nitric oxide (NO) and the subsequent induction of programmed cell death (PCD). Although the nature of this injury may be both preventable and reversible, the underlying mechanisms that
H P Monteiro et al.
Free radical biology & medicine, 28(2), 174-182 (2001-04-03)
Nitric oxide (NO) can participate in cellular signaling. In this study, monoclonal antibodies against proteins from the growth factor-mediated signalling pathway were used to identify a set of 126-, 56-, 43-, and 40-kDa proteins phosphorylated on tyrosine at NO stimulation
D Clark et al.
Molecular plant-microbe interactions : MPMI, 13(12), 1380-1384 (2000-12-06)
We used a variety of nitric oxide (NO) donors to demonstrate that NO inhibits the activities of tobacco catalase and ascorbate peroxidase (APX). This inhibition appears to be reversible because removal of the NO donor led to a significant recovery
Mauricio Di Fulvio et al.
American journal of physiology. Heart and circulatory physiology, 284(5), H1686-H1692 (2003-01-11)
Nitric oxide (NO) donors regulate KCl cotransport (KCC) activity and cotransporter-1 and -3 (KCC1 and KCC3) mRNA expression in sheep erythrocytes and in primary cultures of rat vascular smooth muscle cells (VSMCs), respectively. In this study, we used NONOates as
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