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Acetonitrile

≥99.8% (GC), HPLC grade, isocratic grade, suitable for HPLC, LiChrosolv®

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

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About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
741857
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-835-2
NACRES:
NA.03

product name

Acetonitrile, isocratic grade for liquid chromatography LiChrosolv®

grade

HPLC grade
isocratic

Quality Level

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)
97 hPa ( 20 °C)

product line

LiChrosolv®

Assay

≥99.8% (GC)

form

liquid

autoignition temp.

524 °C
973 °F

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Alkalinity
≤0.0005 meq/g Acidity
≤0.05% Water

evapn. residue

≤4.0 mg/L

transmittance

195 nm, ≥70%
200 nm, ≥90%
240 nm, ≥98%

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

transition temp

flash point 2 °C

density

0.786 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-30°C

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, solvents in"gradient grade" as well as "isocratic grade" are appropriate for use. This enables to minimize the gradient effect of the solvent involved.

Application

Acetonitrile is used as a solvent:
  • In mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) method.
  • In reversed-phase HPLC with an isocratic mode for determining Sudan dyes in chili- and curry-containing foodstuffs.

Features and Benefits

  • microfiltered by 0.2 µm filter
  • high resolution, sensitivity and optimized peak baseline separation

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 4.0 mg/l
Water: ≤ 0.05 %
Acidity: ≤ 0.0005 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 195 nm): ≥ 70 %
Transmission (at 200 nm): ≥ 90 %
Transmission (from 240 nm): ≥ 98 %
Filtered by 0.2 µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC.
L Matysova et al.
Analytical and Bioanalytical Chemistry, 376, 440-443 (2003)
Development of a fast analytical method for the determination of Sudan dyes in chili-and curry-containing foodstuffs by high-performance liquid chromatography- photodiode array detection.
Vanessa C et al.
Journal of Agricultural and Food Chemistry, 54, 639-644 (2006)

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