- Hypoxia enhances antibody-dependent dengue virus infection.
Hypoxia enhances antibody-dependent dengue virus infection.
The EMBO journal (2017-03-23)
Esther Shuyi Gan, Wei Fun Cheong, Kuan Rong Chan, Eugenia Ziying Ong, Xiaoran Chai, Hwee Cheng Tan, Sujoy Ghosh, Markus R Wenk, Eng Eong Ooi
PMID28320741
摘要
Dengue virus (DENV) has been found to replicate in lymphoid organs such as the lymph nodes, spleen, and liver in post-mortem analysis. These organs are known to have low oxygen levels (~0.5-4.5% O