- Recoverable PEG-supported copper catalyst for highly stereocontrolled nitroaldol condensation.
Recoverable PEG-supported copper catalyst for highly stereocontrolled nitroaldol condensation.
Organic letters (2007-05-08)
Marco Bandini, Maurizio Benaglia, Riccardo Sinisi, Simona Tommasi, Achille Umani-Ronchi
PMID17480085
摘要
A new poly(ethylene glycol)-modified DAT2-Cu(OAc)2 complex smoothly catalyzes a base-free nitroaldol condensation in a highly enantioselective manner (ee up to 93%) also in reagent-grade solvent and in the presence of air. Effective recovery and recycling (up to five runs) of supported catalysts are documented.
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