跳转至内容

Solvent dependent reductive defluorination of aliphatic C-F bonds employing Sm(HMDS)2.

Solvent dependent reductive defluorination of aliphatic C-F bonds employing Sm(HMDS)2.

Chemical communications (Cambridge, England) (2013-01-30)

Mario Janjetovic, Annika M Träff, Tobias Ankner, Jenny Wettergren, Göran Hilmersson

摘要

Sm(HMDS)(2) in n-hexane mediates fast cleavage of primary, secondary and tertiary alkyl fluorides in good to excellent yields. In n-hexane Sm(HMDS)(2) exhibits uniquely enhanced reductive ability towards the C-F bond compared to when using THF as solvent.

材料

货号

品牌

产品描述

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 1.0 M in THF

Sigma-Aldrich

六甲基二硅氮烷, reagent grade, ≥99%

Sigma-Aldrich

双(三甲基硅基)氨基钠溶液, 1.0 M in THF

Sigma-Aldrich

双(三甲基硅基)酰胺钾溶液, 1 M in THF

Sigma-Aldrich

六甲基二硅氮烷, ReagentPlus^®, 99.9%

Sigma-Aldrich

双三甲基硅基胺基锂, 97%

Sigma-Aldrich

双(三甲基硅烷基)氨基钾, 95%

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 1 M in toluene

Sigma-Aldrich

双(三甲基硅基)氨基钠, 95%

Sigma-Aldrich

双(三甲基硅基)酰胺钾溶液, 0.5 M in toluene

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 1.5 M in THF

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 1.0 M in hexanes

Sigma-Aldrich

双(三甲基硅基)氨基钠溶液, 40% in THF

Sigma-Aldrich

钐, −40 mesh, 99% trace rare earth metals basis

Supelco

六甲基二硅氮烷, for GC derivatization, LiChropur^™, ≥99.0% (GC)

Sigma-Aldrich

双(三甲基硅基)氨基钠溶液, 0.6 M in toluene

Sigma-Aldrich

三[N,N-双(三甲基甲硅烷基)酰胺]钇

Sigma-Aldrich

六甲基二硅氮烷, produced by Wacker Chemie AG, Burghausen, Germany, ≥97.0% (GC)

Sigma-Aldrich

双(三甲基硅基)酰胺钾溶液, 1.0 M in 2-methyltetrahydrofuran

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 1 M in tert-butyl methyl ether

Sigma-Aldrich

双(三甲基硅基)氨基锂溶液, 0.5 M in 2-methyltetrahydrofuran

Sigma-Aldrich

三[N,N-双(三甲基硅烷)胺]钐(III), 98%