- [Wound healing potential of chitosan and its N-sulfosuccinoyl derivatives].
[Wound healing potential of chitosan and its N-sulfosuccinoyl derivatives].
Izvestiia Akademii nauk. Seriia biologicheskaia (2010-08-31)
T P Alekseeva, A A Rakhmetova, O A Bogoslovskaia, I P Ol'khovskaia, A N Levov, A V Il'ina, V P Varlamov, T A Baĭtukalov, N N Glushchenko
PMID20799640
摘要
Comparative study of chitosan wound healing properties and its synthesized derivatives in MC-100 gel was carried out using the model of experimental full thickness skin wounds. It was determined that N-sulfosuccinoyl chitosan derivatives added into the gel in a concentration of 0.05% possess the higher wound healing activity in comparison with other chitosan derivatives and decrease the half-healing period of wounds 2-3 times in comparison with the control.
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