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生物源
synthetic (organic)
品質等級
化驗
≥97% (HPLC)
形狀
powder
技術
HPLC: suitable
顏色
white to off-white
儲存溫度
2-8°C
SMILES 字串
[Na].CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OP(O)(O)=O)c(C)c(C)c2O1
InChI
1S/C29H51O5P.Na.H/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(34-35(30,31)32)23(5)24(6)28(26)33-29;;/h20-22H,9-19H2,1-8H3,(H2,30,31,32);;
InChI 密鑰
QRLCTLIPEFQSSG-UHFFFAOYSA-N
應用
(±)-α-生育酚磷酸酯二钠盐已被用作抗氧化剂,用于评估其对大鼠海马神经元氧化损伤的保护作用。它还被用于研究其分子机制和跨质膜运输。
生化/生理作用
生育酚(TCP)(维生素E)是一系列(α、β、γ 和δ)手性有机分子,其色原烷醇环苯酚部分的甲基化程度不同。 生育酚是脂溶性抗氧化剂,可保护细胞膜免受氧化损伤。α-生育酚是人类优先吸收的生育酚形式。α-生育酚磷酸酯 (TocP)是与α生育酚乙酸酯、α-生育酚烟酸酯、α-生育酚琥珀酸酯和其他酯化形式一起,作为相似但活性不同的维生素E增补剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Free radical biology & medicine, 50(12), 1794-1800 (2011-03-30)
α-Tocopheryl phosphate (α-TP), a water-soluble analogue of α-tocopherol, is found in humans, animals, and plants. α-TP is resistant to both acid and alkaline hydrolysis and may exert its own function in this form in vivo. In this study, the uptake
Free radical biology & medicine, 39(7), 970-976 (2005-09-06)
We have detected alpha-tocopheryl phosphate in biological tissues including liver and adipose tissue, as well as in a variety of foods, suggesting a ubiquitous presence in animal and plant tissue. Alpha-tocopheryl phosphate is a water-soluble molecule that is resistant to
Molecular nutrition & food research, 54(5), 588-598 (2010-02-20)
Vitamin E is known as the most important lipid antioxidant and is widely used to prevent age-associated diseases. Despite increasing knowledge about human vitamin E metabolism, little is known to justify its widespread use. As meta-analyses revealed even harmful effects
Free radical research, 36(6), 705-709 (2002-08-16)
alpha-Tocopherol is a lipophilic vitamin that exhibits an antioxidative activity. The purpose of this study was to clarify the roles of alpha-tocopherol in the regulation of intracellular glutathione (GSH) levels in HaCaT keratinocytes. When HaCaT keratinocytes were cultivated with alpha-tocopherol
A transient treatment of hippocampal neurons with alpha-tocopherol induces a long-lasting protection against oxidative damage via a genomic action
Free Radical Biology & Medicine (2005)
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