跳转至内容
Merck

T2020

Sigma-Aldrich

(±)-α-生育酚磷酸酯 二钠盐

water-soluble α-tocopherol analog

别名:

Alpha Tocopherol phosphate disodium salt

登录查看公司和协议定价


About This Item

线性分子式:
C29H49O5PNa2
CAS号:
分子量:
554.65
MDL號碼:
分類程式碼代碼:
12352205
eCl@ss:
34058016
PubChem物質ID:
NACRES:
NA.79

生物源

synthetic (organic)

品質等級

化驗

≥97% (HPLC)

形狀

powder

技術

HPLC: suitable

顏色

white to off-white

儲存溫度

2-8°C

SMILES 字串

[Na].CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OP(O)(O)=O)c(C)c(C)c2O1

InChI

1S/C29H51O5P.Na.H/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(34-35(30,31)32)23(5)24(6)28(26)33-29;;/h20-22H,9-19H2,1-8H3,(H2,30,31,32);;

InChI 密鑰

QRLCTLIPEFQSSG-UHFFFAOYSA-N

應用

(±)-α-生育酚磷酸酯二钠盐已被用作抗氧化剂,用于评估其对大鼠海马神经元氧化损伤的保护作用。它还被用于研究其分子机制和跨质膜运输。

生化/生理作用

生育酚(TCP)(维生素E)是一系列(α、β、γ 和δ)手性有机分子,其色原烷醇环苯酚部分的甲基化程度不同。 生育酚是脂溶性抗氧化剂,可保护细胞膜免受氧化损伤。α-生育酚是人类优先吸收的生育酚形式。α-生育酚磷酸酯 (TocP)是与α生育酚乙酸酯、α-生育酚烟酸酯、α-生育酚琥珀酸酯和其他酯化形式一起,作为相似但活性不同的维生素E增补剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Keiko Nishio et al.
Free radical biology & medicine, 50(12), 1794-1800 (2011-03-30)
α-Tocopheryl phosphate (α-TP), a water-soluble analogue of α-tocopherol, is found in humans, animals, and plants. α-TP is resistant to both acid and alkaline hydrolysis and may exert its own function in this form in vivo. In this study, the uptake
Robert Gianello et al.
Free radical biology & medicine, 39(7), 970-976 (2005-09-06)
We have detected alpha-tocopheryl phosphate in biological tissues including liver and adipose tissue, as well as in a variety of foods, suggesting a ubiquitous presence in animal and plant tissue. Alpha-tocopheryl phosphate is a water-soluble molecule that is resistant to
Marc Birringer
Molecular nutrition & food research, 54(5), 588-598 (2010-02-20)
Vitamin E is known as the most important lipid antioxidant and is widely used to prevent age-associated diseases. Despite increasing knowledge about human vitamin E metabolism, little is known to justify its widespread use. As meta-analyses revealed even harmful effects
Hitoshi Masaki et al.
Free radical research, 36(6), 705-709 (2002-08-16)
alpha-Tocopherol is a lipophilic vitamin that exhibits an antioxidative activity. The purpose of this study was to clarify the roles of alpha-tocopherol in the regulation of intracellular glutathione (GSH) levels in HaCaT keratinocytes. When HaCaT keratinocytes were cultivated with alpha-tocopherol
A transient treatment of hippocampal neurons with alpha-tocopherol induces a long-lasting protection against oxidative damage via a genomic action
de Jesus Ferreira MC, et al.
Free Radical Biology & Medicine (2005)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门