SML1147

IQ-1

≥95% (HPLC)

• 别名: 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
• 经验公式（希尔记法）: C₂₁H₂₂N₄O₂
• CAS号: 331001-62-8
• 分子量: 362.42
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825681
• NACRES: NA.77

属性

• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: yellow to orange
• 溶解度: DMSO: 10 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: CC(C1=CC=C(N=N/C(C(N)=O)=C2NC(C)(C)CC3=C/2C=CC=C3)C=C1)=O
• InChI: 1S/C21H22N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,23H,12H2,1-3H3,(H2,22,27)/b19-18+,25-24?
• InChI 密鑰: ZXSRRUROLCGTBS-ASEVQSCHSA-N

说明

生化／生理作用

IQ-1 enhances β-catenin/CBP interactions and blocks β-catenin/p300 driven transcription, which enables mouse embryonic stem cells (ESCs) to be maintained in an undifferentiated pluripotent state, allowing expansion and self-renewal of mouse ESC populations.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable