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Merck

SMB01045

Sigma-Aldrich

Isoliquiritin

≥90% (LC/MS-ELSD)

别名:

4-beta-D-glucopyranosyloxy-2′,4′-dihydroxy-trans-chalcone, Isoliquiritoside

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About This Item

经验公式(希尔记法):
C21H22O9
CAS号:
分子量:
418.39
MDL號碼:
分類程式碼代碼:
12352205
NACRES:
NA.25

生物源

plant

化驗

≥90% (LC/MS-ELSD)

形狀

solid

分子量

418.39

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

InChI

1S/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1

InChI 密鑰

YNWXJFQOCHMPCK-LXGDFETPSA-N

一般說明

Isoliquiritin, also known as Isoliquiritoside, is a flavonoid belongs to the class of dihydrochalcones commonly available from Glycyrrhiza Sp. plants. This plant metabolite exhibits various biological activities, including antioxidant, antifungal, anti-HIV, anticancer properties.

應用

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化/生理作用

Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens.

特點和優勢

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

其他說明

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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